Matrigel influences morphology and cathepsin B distribution of prostate cancer PC3 cells
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چکیده
منابع مشابه
Matrigel influences morphology and cathepsin B distribution of prostate cancer PC3 cells.
Increases in expression and activity of matrix-degrading enzymes such as the cysteine proteinases cathepsins B and L, and abnormal levels of their inhibitors, the cystatins, are associated with tumor cell invasion and metastasis. Environmental conditions have been shown to be causative factors in the development of a metastatic/invasive phenotype. We hypothesized that cell-matrix interactions a...
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We studied the effect of doxorubicin on the production of hydrogen peroxide by PC3 human prostate cancer cells, using a sensitive assay based on aminotriazole-mediated inhibition of catalase. PC3 cells exposed to increasing concentrations of doxorubicin had an increase in intracellular hydrogen peroxide that was concentration-dependent up to 1 microM doxorubicin. The apparent hydrogen peroxide ...
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ژورنال
عنوان ژورنال: Oncology Reports
سال: 2006
ISSN: 1021-335X,1791-2431
DOI: 10.3892/or.16.2.313